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SaeR Binds a Consensus Sequence within Virulence Gene Promoters to Advance USA300 Pathogenesis

This investigation examines the role of the SaeR/S two-component system in USA300, a prominent circulating clone of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). Using a saeR/S isogenic deletion mutant of USA300 (USA300ΔsaeR/S) in murine models of sepsis and soft-tissue...

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Détails bibliographiques
Auteurs principaux: Nygaard, Tyler K., Pallister, Kyler B., Ruzevich, Peter, Griffith, Shannon, Vuong, Cuong, Voyich, Jovanka M.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798008/
https://ncbi.nlm.nih.gov/pubmed/20001858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/649570
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