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Contribution of hla Regulation by SaeR to Staphylococcus aureus USA300 Pathogenesis

The SaeRS two-component system in Staphylococcus aureus is critical for regulation of many virulence genes, including hla, which encodes alpha-toxin. However, the impact of regulation of alpha-toxin by Sae on S. aureus pathogenesis has not been directly addressed. Here, we mutated the SaeR-binding s...

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Publicat a:Infect Immun
Autors principals: Gudeta, Dereje D., Lei, Mei G., Lee, Chia Y.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704604/
https://ncbi.nlm.nih.gov/pubmed/31209148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00231-19
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