Use of BODIPY-Labeled ATP Analogues in the Development and Validation of a Fluorescence Polarization-Based Assay for Screening of Kinase Inhibitors

[Image: see text] The screening of compound libraries to identify small-molecule modulators of specific biological targets is crucial in the process for the discovery of novel therapeutics and molecular probes. Considering the need for simple single-tool assay technologies with which one could monit...

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Pubblicato in:ACS Omega
Autori principali: Moreira, Bernardo Pereira, Armstrong, Tom, Batista, Izabella Cristina Andrade, Clemente Tavares, Naiara, Pires, Camilla Valente, de Moraes Mourão, Marina, Falcone, Franco H., Dekker, Lodewijk V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2020
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191558/
https://ncbi.nlm.nih.gov/pubmed/32363258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03344
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