TRAF4 acts as a fate checkpoint to regulate the adipogenic differentiation of MSCs by activating PKM2

BACKGROUND: Mesenchymal stem cells (MSCs) selectively differentiate into adipocytes or osteoblasts, and several molecules control the fate determination of MSCs. Understanding these key checkpoints greatly contributes to the ability to induce specific MSC differentiation for clinical applications. I...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Cen, Shuizhong, Li, Jinteng, Cai, Zhaopeng, Pan, Yiqian, Sun, Zehang, Li, Zhaofeng, Ye, Guiwen, Zheng, Guan, Li, Ming, Liu, Wenjie, Yu, Wenhui, Wang, Shan, Xie, Zhongyu, Wang, Peng, Shen, Huiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191261/
https://ncbi.nlm.nih.gov/pubmed/32268273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102722
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