TRAF4 acts as a fate checkpoint to regulate the adipogenic differentiation of MSCs by activating PKM2

BACKGROUND: Mesenchymal stem cells (MSCs) selectively differentiate into adipocytes or osteoblasts, and several molecules control the fate determination of MSCs. Understanding these key checkpoints greatly contributes to the ability to induce specific MSC differentiation for clinical applications. I...

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Vydáno v:EBioMedicine
Hlavní autoři: Cen, Shuizhong, Li, Jinteng, Cai, Zhaopeng, Pan, Yiqian, Sun, Zehang, Li, Zhaofeng, Ye, Guiwen, Zheng, Guan, Li, Ming, Liu, Wenjie, Yu, Wenhui, Wang, Shan, Xie, Zhongyu, Wang, Peng, Shen, Huiyong
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191261/
https://ncbi.nlm.nih.gov/pubmed/32268273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102722
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