Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model

Seizures often herald the clinical appearance of gliomas or appear at later stages. Dissecting their precise evolution and cellular pathogenesis in brain malignancies could inform the development of staged therapies for these highly pharmaco-resistant epilepsies. Studies in immunodeficient xenograft...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Hatcher, Asante, Yu, Kwanha, Meyer, Jochen, Aiba, Isamu, Deneen, Benjamin, Noebels, Jeffrey L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190940/
https://ncbi.nlm.nih.gov/pubmed/32250339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133316
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