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Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model

Seizures often herald the clinical appearance of gliomas or appear at later stages. Dissecting their precise evolution and cellular pathogenesis in brain malignancies could inform the development of staged therapies for these highly pharmaco-resistant epilepsies. Studies in immunodeficient xenograft...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hatcher, Asante, Yu, Kwanha, Meyer, Jochen, Aiba, Isamu, Deneen, Benjamin, Noebels, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190940/
https://ncbi.nlm.nih.gov/pubmed/32250339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133316
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