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HGG-10. THE PI3K/mTOR PATHWAY CONTRIBUTES TO SEX DIFFERENCES IN GLIOBLASTOMA

Glioblastoma (GBM) occurs more commonly in males but female GBM patients survive significantly longer. In our efforts to identify the mechanisms underlying these differences, we found that EGFR amplification and increased mTOR phosphorylation worsen outcome for male, but not female patients. In orde...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Sponagel, Jasmin, Yu, Kwanha, Ippolito, Joseph, Deneen, Benjamin, Rubin, Josh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012180/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.282
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