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Local microvascular leakage promotes trafficking of activated neutrophils to remote organs

Increased microvascular permeability to plasma proteins and neutrophil emigration are hallmarks of innate immunity and key features of numerous inflammatory disorders. Although neutrophils can promote microvascular leakage, the impact of vascular permeability on neutrophil trafficking is unknown. He...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Owen-Woods, Charlotte, Joulia, Régis, Barkaway, Anna, Rolas, Loïc, Ma, Bin, Nottebaum, Astrid Fee, Arkill, Kenton P., Stein, Monja, Girbl, Tamara, Golding, Matthew, Bates, David O., Vestweber, Dietmar, Voisin, Mathieu-Benoit, Nourshargh, Sussan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190919/
https://ncbi.nlm.nih.gov/pubmed/31971917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133661
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