Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury

Although CEACAM1 (CC1) glycoprotein resides at the interface of immune liver injury and metabolic homeostasis, its role in orthotopic liver transplantation (OLT) remains elusive. We aimed to determine whether/how CEACAM1 signaling may affect hepatic ischemia-reperfusion injury (IRI) and OLT outcomes...

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Vydáno v:J Clin Invest
Hlavní autoři: Nakamura, Kojiro, Kageyama, Shoichi, Kaldas, Fady M., Hirao, Hirofumi, Ito, Takahiro, Kadono, Kentaro, Dery, Kenneth J., Kojima, Hidenobu, Gjertson, David W., Sosa, Rebecca A., Kujawski, Maciej, Busuttil, Ronald W., Reed, Elaine F., Kupiec-Weglinski, Jerzy W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190917/
https://ncbi.nlm.nih.gov/pubmed/32027621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133142
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