Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury

Although CEACAM1 (CC1) glycoprotein resides at the interface of immune liver injury and metabolic homeostasis, its role in orthotopic liver transplantation (OLT) remains elusive. We aimed to determine whether/how CEACAM1 signaling may affect hepatic ischemia-reperfusion injury (IRI) and OLT outcomes...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Nakamura, Kojiro, Kageyama, Shoichi, Kaldas, Fady M., Hirao, Hirofumi, Ito, Takahiro, Kadono, Kentaro, Dery, Kenneth J., Kojima, Hidenobu, Gjertson, David W., Sosa, Rebecca A., Kujawski, Maciej, Busuttil, Ronald W., Reed, Elaine F., Kupiec-Weglinski, Jerzy W.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190917/
https://ncbi.nlm.nih.gov/pubmed/32027621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133142
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