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Cyclic tensile strain facilitates ossification of the cervical posterior longitudinal ligament via increased Indian hedgehog signaling

The pathomechanisms of initiation and progression of ossification of the posterior longitudinal ligament (OPLL) are unclear. Indian hedgehog (Ihh) and related signaling molecules are key factors in normal enchondral ossification. The purpose of this study is to investigate the contribution of mechan...

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書目詳細資料
發表在:Sci Rep
Main Authors: Sugita, Daisuke, Nakajima, Hideaki, Kokubo, Yasuo, Takeura, Naoto, Yayama, Takafumi, Matsumine, Akihiko
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190672/
https://ncbi.nlm.nih.gov/pubmed/32350355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64304-w
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