IL-2 enhances ex vivo–expanded regulatory T-cell persistence after adoptive transfer

As regulatory T cell (Treg) adoptive therapy continues to develop clinically, there is a need to determine which immunomodulatory agents pair most compatibly with Tregs to enable persistence and stabilize suppressor function. Prior work has shown that mechanistic target of rapamycin inhibition can i...

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Detalles Bibliográficos
Publicado en:Blood Adv
Main Authors: Furlan, Scott N., Singh, Karnail, Lopez, Christina, Tkachev, Victor, Hunt, Daniel Joel, Hibbard, James, Betz, Kayla M., Blazar, Bruce R., Trapnell, Cole, Kean, Leslie S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2020
Assuntos:
Immunobiology and Immunotherapy
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189290/
https://ncbi.nlm.nih.gov/pubmed/32311015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001248
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