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Amino acid 159 of the envelope protein affects viral replication and T-cell infiltration by West Nile virus in intracranial infection

West Nile virus (WNV) is an important cause of viral encephalitis in birds and animals, including humans. Amino acid 159 of the envelope (E) protein is reportedly implicated in the different levels of neurovirulence in mice infected with WNV NY99 or Eg101. We investigated the role of amino acid 159...

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Publicado en:Sci Rep
Autores principales: Kobayashi, Shintaro, Kaneko, Chisato, Kawakami, Ryoko, Hasebe, Rie, Sawa, Hirofumi, Yoshii, Kentaro, Kariwa, Hiroaki
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189269/
https://ncbi.nlm.nih.gov/pubmed/32346055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64199-7
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