Engineered niches support the development of human dendritic cells in humanized mice

Classical dendritic cells (cDCs) are rare sentinel cells specialized in the regulation of adaptive immunity. Modeling cDC development is crucial to study cDCs and harness their therapeutic potential. Here we address whether cDCs could differentiate in response to trophic cues delivered by mesenchyma...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Anselmi, Giorgio, Vaivode, Kristine, Dutertre, Charles-Antoine, Bourdely, Pierre, Missolo-Koussou, Yoann, Newell, Evan, Hickman, Oliver, Wood, Kristie, Saxena, Alka, Helft, Julie, Ginhoux, Florent, Guermonprez, Pierre
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189247/
https://ncbi.nlm.nih.gov/pubmed/32345968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15937-y
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