5-FU-Induced Upregulation of Exosomal PD-L1 Causes Immunosuppression in Advanced Gastric Cancer Patients

Although the cytotoxic chemotherapeutic agent 5-fluorouracil (5-FU) is generally considered to directly kill cancer cells and exert immunostimulatory effects in advanced gastric cancer, accumulating evidence indicates that it upregulates the expression of PD-L1, a representative immune checkpoint bl...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Zhang, Min, Fan, Yibo, Che, Xiaofang, Hou, Kezuo, Zhang, Chaoxu, Li, Ce, Wen, Ti, Wang, Shuo, Cheng, Yu, Liu, Yunpeng, Qu, Xiujuan
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188923/
https://ncbi.nlm.nih.gov/pubmed/32391259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00492
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