4-phenylbutyric acid promotes migration of gastric cancer cells by histone deacetylase inhibition-mediated IL-8 upregulation

Histone acetylation is regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs). It is associated with gene transcription and expression. 4-Phenylbutyric acid (4-PBA), an HDAC inhibitor (HDACi), can inhibit cancer cell proliferation by increasing the level of histone acetylati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Epigenetics
Prif Awduron: Shi, Xiaonan, Gong, Libao, Liu, Yunpeng, Hou, Kezuo, Fan, Yibo, Li, Ce, Wen, Ti, Qu, Xiujuan, Che, Xiaofang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2019
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574398/
https://ncbi.nlm.nih.gov/pubmed/31814524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1700032
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