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Chitinase 3-like 1 is neurotoxic in primary cultured neurons

Chitinase 3-like 1 (CHI3L1) is known to play a role as prognostic biomarker in the early stages of multiple sclerosis (MS), and patients with high cerebrospinal fluid CHI3L1 levels have an increased risk for the development of neurological disability. Here, we investigated its potential neurotoxic e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matute-Blanch, Clara, Calvo-Barreiro, Laura, Carballo-Carbajal, Iria, Gonzalo, Ricardo, Sanchez, Alex, Vila, Miquel, Montalban, Xavier, Comabella, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188887/
https://ncbi.nlm.nih.gov/pubmed/32346016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64093-2
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