Chitinase 3-like 1 is neurotoxic in primary cultured neurons

Chitinase 3-like 1 (CHI3L1) is known to play a role as prognostic biomarker in the early stages of multiple sclerosis (MS), and patients with high cerebrospinal fluid CHI3L1 levels have an increased risk for the development of neurological disability. Here, we investigated its potential neurotoxic e...

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Published in:Sci Rep
Main Authors: Matute-Blanch, Clara, Calvo-Barreiro, Laura, Carballo-Carbajal, Iria, Gonzalo, Ricardo, Sanchez, Alex, Vila, Miquel, Montalban, Xavier, Comabella, Manuel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188887/
https://ncbi.nlm.nih.gov/pubmed/32346016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64093-2
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