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Chitinase 3-like 1 is neurotoxic in primary cultured neurons

Chitinase 3-like 1 (CHI3L1) is known to play a role as prognostic biomarker in the early stages of multiple sclerosis (MS), and patients with high cerebrospinal fluid CHI3L1 levels have an increased risk for the development of neurological disability. Here, we investigated its potential neurotoxic e...

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Publicat a:Sci Rep
Autors principals: Matute-Blanch, Clara, Calvo-Barreiro, Laura, Carballo-Carbajal, Iria, Gonzalo, Ricardo, Sanchez, Alex, Vila, Miquel, Montalban, Xavier, Comabella, Manuel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188887/
https://ncbi.nlm.nih.gov/pubmed/32346016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64093-2
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