Caloric restriction reverses left ventricular hypertrophy through the regulation of cardiac iron homeostasis in impaired leptin signaling mice

Leptin-deficient and leptin-resistant mice manifest obesity, insulin resistance, and left ventricular hypertrophy (LVH); however, LVH’s mechanisms are not fully understood. Cardiac iron dysregulation has been recently implicated in cardiomyopathy. Here we investigated the protective effects of calor...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: An, Hyeong Seok, Lee, Jong Youl, Choi, Eun Bee, Jeong, Eun Ae, Shin, Hyun Joo, Kim, Kyung Eun, Park, Kyung-Ah, Jin, Zhen, Lee, Jung Eun, Koh, Jin Sin, Kwak, Woori, Kim, Won-Ho, Roh, Gu Seob
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188880/
https://ncbi.nlm.nih.gov/pubmed/32346034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64201-2
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge