The Role of SHIP1 on Apoptosis and Autophagy in the Adipose Tissue of Obese Mice

Obesity-induced adipocyte apoptosis promotes inflammation and insulin resistance. Src homology domain-containing inositol 5′-phosphatase 1 (SHIP1) is a key factor of apoptosis and inflammation. However, the role of SHIP1 in obesity-induced adipocyte apoptosis and autophagy is unclear. We found that...

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Bibliographische Detailangaben
Hauptverfasser: Jae Hun Jeong, Eun Bee Choi, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Gyeongah Park, Eun Ae Jeong, Hyun Joo Shin, Jaewoong Lee, Kyung Eun Kim, Gu Seob Roh
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-09-01
Schriftenreihe:International Journal of Molecular Sciences
Schlagworte:
SHIP1
macrophage
apoptosis
autophagy
adipose tissue
obesity
Online Zugang:https://www.mdpi.com/1422-0067/21/19/7225
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