A Dual TLR7/TLR9 Inhibitor HJ901 Inhibits ABC-DLBCL Expressing the MyD88 L265P Mutation

Diffuse large B cell lymphoma (DLBCL) is associated with aggressive clinical cases and poor prognosis despite recent advances in disease treatment. In activated B-cell-like (ABC)-DLBCL, the most severe damaged signaling pathways converge to aberrantly activate the Toll-like receptor (TLR) 7/9/MyD88...

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Udgivet i:Front Cell Dev Biol
Main Authors: An, Beiying, Zhu, Shan, Li, Tete, Wu, Jing, Zang, Guoxia, Lv, Xinping, Qiao, Yuan, Huang, Jing, Shao, Yan, Cui, Jiuwei, Liu, Yong-Jun, Chen, Jingtao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188833/
https://ncbi.nlm.nih.gov/pubmed/32391356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00262
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