Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis

OBJECTIVES: IL-36 agonists are pro-inflammatory cytokines involved in the pathogenesis of psoriasis. However, their role in the pathogenesis of arthritis and treatment response to DMARDs in PsA remains uncertain. Therefore, we investigated the IL-36 axis in the synovium of early, treatment-naïve PsA...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Rheumatology (Oxford)
Prif Awduron: Boutet, Marie-Astrid, Nerviani, Alessandra, Lliso-Ribera, Gloria, Lucchesi, Davide, Prediletto, Edoardo, Ghirardi, Giulia Maria, Goldmann, Katriona, Lewis, Myles, Pitzalis, Costantino
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Clinical Science
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188345/
https://ncbi.nlm.nih.gov/pubmed/31504934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kez358
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