A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients

Objectives: To assess whether the histopathological features of the synovium before starting treatment with the TNFi certolizumab-pegol could predict clinical outcome and examine the modulation of histopathology by treatment. Methods: Thirty-seven RA patients fulfilling UK NICE guidelines for biolog...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Nerviani, Alessandra, Di Cicco, Maria, Mahto, Arti, Lliso-Ribera, Gloria, Rivellese, Felice, Thorborn, Georgina, Hands, Rebecca, Bellan, Mattia, Mauro, Daniele, Boutet, Marie-Astrid, Giorli, Giovanni, Lewis, Myles, Kelly, Stephen, Bombardieri, Michele, Humby, Frances, Pitzalis, Costantino
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214807/
https://ncbi.nlm.nih.gov/pubmed/32431716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00845
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