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Evaluation of Concordance Between Deficient Mismatch Repair and Microsatellite Instability Testing and Their Association with Clinicopathological Features in Colorectal Cancer

BACKGROUND: Microsatellite instability (MSI) is one of the most important molecular characteristics of colorectal cancer (CRC), which mainly results from defective DNA mismatch repair (MMR). This study was performed to investigate the concordance between deficient MMR and MSI testing, and to evaluat...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Bai, Huili, Wang, Rong, Cheng, Wei, Shen, Yifan, Li, Haijun, Xia, Wei, Ding, Zhenglin, Zhang, Yuhong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187941/
https://ncbi.nlm.nih.gov/pubmed/32425600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S248069
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