Comparable In Vitro Activities of Second-Generation HIV-1 Integrase Strand Transfer Inhibitors (INSTIs) on HIV-1 Clinical Isolates with INSTI Resistance Mutations

Second-generation HIV-1 integrase strand transfer inhibitors (INSTIs) dolutegravir (DTG), bictegravir (BIC), and cabotegravir (CAB) showed a high genetic barrier to resistance and limited cross-resistance with first-generation INSTIs raltegravir (RAL) and elvitegravir (EVG). In this study, DTG, BIC,...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Saladini, Francesco, Giannini, Alessia, Boccuto, Adele, Dragoni, Filippo, Appendino, Alice, Albanesi, Edoardo, Vicenti, Ilaria, Zazzi, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Susceptibility
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187585/
https://ncbi.nlm.nih.gov/pubmed/31611362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01717-19
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