Mesencephalic Astrocyte‐Derived Neurotrophic Factor Inhibits Liver Cancer Through Small Ubiquitin‐Related Modifier (SUMO)ylation‐Related Suppression of NF‐κB/Snail Signaling Pathway and Epithelial‐Mesenchymal Transition

BACKGROUND AND AIMS: Endoplasmic reticulum (ER) stress is associated with liver inflammation and hepatocellular carcinoma (HCC). However, how ER stress links inflammation and HCC remains obscure. Mesencephalic astrocyte‐derived neurotrophic factor (MANF) is an ER stress‐inducible secretion protein t...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Liu, Jun, Wu, Zhengsheng, Han, Dan, Wei, Chuansheng, Liang, Yanyan, Jiang, Tongcui, Chen, Lu, Sha, Manqi, Cao, Yajie, Huang, Fan, Geng, Xiaoping, Yu, Jishuang, Shen, Yujun, Wang, Hua, Feng, Lijie, Wang, Dong, Fang, Shengyun, Wang, Siying, Shen, Yuxian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187412/
https://ncbi.nlm.nih.gov/pubmed/31469428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30917
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