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Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Involved in Inflammation by Negatively Regulating the NF-κB Pathway

Inflammation can cause endoplasmic reticulum (ER) stress and therefore activates the unfolded protein response (UPR). ER stress and the consequent UPR have the potential to activate NF-κB. However, the factors mediating the crosstalk between ER stress and the NF-κB pathway remain unclear. Here, we d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Lijian, Feng, Lijie, Wang, Xia, Du, Jian, Chen, Ying, Yang, Wen, Zhou, Chengyue, Cheng, Li, Shen, Yujun, Fang, Shengyun, Li, Jun, Shen, Yuxian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313098/
https://ncbi.nlm.nih.gov/pubmed/25640174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08133
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