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Optimizing beta cell function through mesenchymal stromal cell‐mediated mitochondria transfer

Pretransplant islet culture is associated with the loss of islet cell mass and insulin secretory function. Insulin secretion from islet β‐cells is primarily controlled by mitochondrial ATP generation in response to elevations in extracellular glucose. Coculture of islets with mesenchymal stromal cel...

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Détails bibliographiques
Publié dans:Stem Cells
Auteurs principaux: Rackham, Chloe L., Hubber, Ella L., Czajka, Anna, Malik, Afshan N., King, Aileen J. F., Jones, Peter M.
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187381/
https://ncbi.nlm.nih.gov/pubmed/31912945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3134
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