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Optimizing beta cell function through mesenchymal stromal cell‐mediated mitochondria transfer
Pretransplant islet culture is associated with the loss of islet cell mass and insulin secretory function. Insulin secretion from islet β‐cells is primarily controlled by mitochondrial ATP generation in response to elevations in extracellular glucose. Coculture of islets with mesenchymal stromal cel...
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| Publié dans: | Stem Cells |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley & Sons, Inc.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7187381/ https://ncbi.nlm.nih.gov/pubmed/31912945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3134 |
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