Isoindoline‐Based Nitroxides as Bioresistant Spin Labels for Protein Labeling through Cysteines and Alkyne‐Bearing Noncanonical Amino Acids

Electron paramagnetic resonance (EPR) spectroscopy in combination with site‐directed spin labeling (SDSL) is a powerful tool in protein structural research. Nitroxides are highly suitable spin labeling reagents, but suffer from limited stability, particularly in the cellular environment. Herein we p...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Braun, Theresa Sophie, Widder, Pia, Osswald, Uwe, Groß, Lina, Williams, Lara, Schmidt, Moritz, Helmle, Irina, Summerer, Daniel, Drescher, Malte
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187341/
https://ncbi.nlm.nih.gov/pubmed/31657498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900537
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