Zika virus envelope nanoparticle antibodies protect mice without risk of disease enhancement

BACKGROUND: Zika virus (ZIKV), an arbovirus capable of causing neurological abnormalities, is a recognised human pathogen, for which a vaccine is required. As ZIKV antibodies can mediate antibody-dependent enhancement (ADE) of dengue virus (DENV) infection, a ZIKV vaccine must not only protect again...

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Shukla, Rahul, Shanmugam, Rajgokul K., Ramasamy, Viswanathan, Arora, Upasana, Batra, Gaurav, Acklin, Joshua A., Krammer, Florian, Lim, Jean K., Swaminathan, Sathyamangalam, Khanna, Navin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186774/
https://ncbi.nlm.nih.gov/pubmed/32305868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102738
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