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Detecting Genotype-Population Interaction Effects by Ancestry Principal Components

Heterogeneity in the phenotypic mean and variance across populations is often observed for complex traits. One way to understand heterogeneous phenotypes lies in uncovering heterogeneity in genetic effects. Previous studies on genetic heterogeneity across populations were typically based on discrete...

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Veröffentlicht in:Front Genet
Hauptverfasser: Yu, Chenglong, Ni, Guiyan, van der Werf, Julius, Lee, S. Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186421/
https://ncbi.nlm.nih.gov/pubmed/32373165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00379
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