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LRRK2 Expression in Normal and Pathologic Human Brain and in Human Cell Lines

Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) have been recently identified in families with autosomal-dominant late-onset Parkinson disease. We report that by reverse transcriptase-polymerase chain reaction, the mRNA of LRRK2 is expressed in soluble extracts of human brain, liver, and...

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Publicat a:J Neuropathol Exp Neurol
Autors principals: Miklossy, Judith, Arai, Tetsuaki, Guo, Jian-Ping, Klegeris, Andis, Yu, Sheng, McGeer, Edith G., McGeer, Patrick L.
Format: Artigo
Idioma:Inglês
Publicat: American Association of Neuropathologists, Inc. 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185781/
https://ncbi.nlm.nih.gov/pubmed/17021400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.jnen.0000235121.98052.54
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