Therapeutic opportunities of small interfering RNA

Formation of small interfering RNA (siRNA) occurs in two steps involving binding of the RNA nucleases to a large double‐stranded RNA (dsRNA) and its cleavage into fragments called siRNA. In the second step, these siRNAs join a multinuclease complex, which degrades the homologous single‐stranded mRNA...

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Bibliografski detalji
Izdano u:Fundam Clin Pharmacol
Glavni autori: Goyal, Bhoomika R., Patel, Mayur M., Soni, Mithil K., Bhadada, Shraddha V.
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2009
Teme:
Review Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185611/
https://ncbi.nlm.nih.gov/pubmed/19709318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1472-8206.2009.00694.x
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