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Therapeutic opportunities of small interfering RNA
Formation of small interfering RNA (siRNA) occurs in two steps involving binding of the RNA nucleases to a large double‐stranded RNA (dsRNA) and its cleavage into fragments called siRNA. In the second step, these siRNAs join a multinuclease complex, which degrades the homologous single‐stranded mRNA...
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| Publicado no: | Fundam Clin Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7185611/ https://ncbi.nlm.nih.gov/pubmed/19709318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1472-8206.2009.00694.x |
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