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Efficient Construction of a Complete Index for Pan-Genomics Read Alignment
Short-read aligners predominantly use the FM-index, which is easily able to index one or a few human genomes. However, it does not scale well to indexing collections of thousands of genomes. Driving this issue are the two chief components of the index: (1) a rank data structure over the Burrows–Whee...
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| Pubblicato in: | J Comput Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Mary Ann Liebert, Inc., publishers
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7185338/ https://ncbi.nlm.nih.gov/pubmed/32181684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2019.0309 |
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