Short Communication: Metformin Reduces CD4 T Cell Exhaustion in HIV-Infected Adults on Suppressive Antiretroviral Therapy

Increased negative immune checkpoint receptors (NCR) on T cells are linked to T cell exhaustion, dysfunctional effector responses, and HIV viral persistence. Metformin, an oral hypoglycemic agent used for diabetes, may have previously unrecognized beneficial immunologic effects. Using cryopreserved...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Shikuma, Cecilia M., Chew, Glen M., Kohorn, Lindsay, Souza, Scott A., Chow, Dominic, SahBandar, Ivo Novita, Park, Eun-Young, Hanks, Nancy, Gangcuangco, Louie Mar A., Gerschenson, Mariana, Ndhlovu, Lishomwa C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Outcomes Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185314/
https://ncbi.nlm.nih.gov/pubmed/31731885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2019.0078
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados