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Dendritic spine pathology and thrombospondin-1 deficits in Down syndrome

Abnormal dendritic spine structure and function is one of the most prominent features associated with neurodevelopmental disorders including Down syndrome (DS). Defects in both spine morphology and spine density may underlie alterations in neuronal and synaptic plasticity, ultimately affecting cogni...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Torres, Maria D, Garcia, Octavio, Tang, Cindy, Busciglio, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185223/
https://ncbi.nlm.nih.gov/pubmed/28965914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.09.025
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