A novel germline gain-of-function HIF2A mutation in hepatocellular carcinoma with polycythemia

Hypoxia-inducible factors (HIFs) regulate oxygen sensing and expression of genes involved in angiogenesis and erythropoiesis. Polycythemia has been observed in patients with hepatocellular carcinoma (HCC), but the underlying molecular basis remains unknown. Liver tissues from 302 HCC patients, inclu...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Yu, Jiong, Shi, Xiaowei, Yang, Chunzhang, Bullova, Petra, Hong, Christopher S., Nesvick, Cody L., Dmitriev, Pauline, Pacak, Karel, Zhuang, Zhengping, Cao, Hongcui, Li, Lanjuan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185130/
https://ncbi.nlm.nih.gov/pubmed/32235007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102967
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