Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways

Esophageal carcinoma (EsC) is a clinically challenging neoplastic disease. Genistein, a natural isoflavone product, has anti-tumor properties. Through in vitro and in vivo studies, we found that genistein suppressed EsC cell proliferation in a time- and concentration-dependent manner. In addition, g...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Gao, Jing, Xia, Rongmu, Chen, Jianbo, Luo, Xianyang, Ke, Chunlin, Ren, Caihong, Li, Jiayi, Mi, Yanjun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185096/
https://ncbi.nlm.nih.gov/pubmed/32276266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103019
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