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MicroRNA-4290 suppresses PDK1-mediated glycolysis to enhance the sensitivity of gastric cancer cell to cisplatin

The development of chemotherapy resistance significantly impairs the efficiency of chemotherapy, but the underlying mechanisms of chemotherapy resistance in gastric cancer (GC) are complicated and still need to be further explored. Here, we aimed to reveal the effects of miR-4290/PDK1 (pyruvate dehy...

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Dades bibliogràfiques
Publicat a:Braz J Med Biol Res
Autors principals: Qian, Yan, Wu, Xu, Wang, Haixiao, Hou, Guowei, Han, Xiao, Song, Wei
Format: Artigo
Idioma:Inglês
Publicat: Associação Brasileira de Divulgação Científica 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184963/
https://ncbi.nlm.nih.gov/pubmed/32321153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20209330
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