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MicroRNA-4290 suppresses PDK1-mediated glycolysis to enhance the sensitivity of gastric cancer cell to cisplatin

The development of chemotherapy resistance significantly impairs the efficiency of chemotherapy, but the underlying mechanisms of chemotherapy resistance in gastric cancer (GC) are complicated and still need to be further explored. Here, we aimed to reveal the effects of miR-4290/PDK1 (pyruvate dehy...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Braz J Med Biol Res
Κύριοι συγγραφείς: Qian, Yan, Wu, Xu, Wang, Haixiao, Hou, Guowei, Han, Xiao, Song, Wei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Associação Brasileira de Divulgação Científica 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184963/
https://ncbi.nlm.nih.gov/pubmed/32321153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20209330
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