Low-Abundance Drug-Resistant HIV-1 Variants in Antiretroviral Drug-Naive Individuals: A Systematic Review of Detection Methods, Prevalence, and Clinical Impact

BACKGROUND: The presence of high-abundance drug-resistant HIV-1 jeopardizes success of antiretroviral therapy (ART). Despite numerous investigations, the clinical impact of low-abundance drug-resistant HIV-1 variants (LA-DRVs) at levels <15%–25% of the virus population in antiretroviral (ARV) dru...

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Bibliografski detalji
Izdano u:J Infect Dis
Glavni autori: Mbunkah, Herbert A, Bertagnolio, Silvia, Hamers, Raph L, Hunt, Gillian, Inzaule, Seth, Rinke De Wit, Tobias F, Paredes, Roger, Parkin, Neil T, Jordan, Michael R, Metzner, Karin J
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Reviews
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184901/
https://ncbi.nlm.nih.gov/pubmed/31809534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz650
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