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Differences in stability and calcium sensitivity of the Ig domains in titin's N2A region

Titin is a large filamentous protein that spans half a sarcomere, from Z‐disk to M‐line. The N2A region within the titin molecule exists between the proximal immunoglobulin (Ig) region and the PEVK region and protein–protein interactions involving this region are required for normal muscle function....

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Bibliographische Detailangaben
Veröffentlicht in:Protein Sci
Hauptverfasser: Kelly, Colleen M., Manukian, Sophia, Kim, Emily, Gage, Matthew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184778/
https://ncbi.nlm.nih.gov/pubmed/32112607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3848
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