Intra-CSF AAV9 and AAVrh10 Administration in Nonhuman Primates: Promising Routes and Vectors for Which Neurological Diseases?

The identification of the most efficient method for whole central nervous system targeting that is translatable to humans and the safest route of adeno-associated virus (AAV) administration is a major concern for future applications in clinics. Additionally, as many AAV serotypes were identified for...

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Détails bibliographiques
Publié dans:Mol Ther Methods Clin Dev
Auteurs principaux: Bey, Karim, Deniaud, Johan, Dubreil, Laurence, Joussemet, Béatrice, Cristini, Joseph, Ciron, Carine, Hordeaux, Juliette, Le Boulc’h, Morwenn, Marche, Kevin, Maquigneau, Maud, Guilbaud, Michaël, Moreau, Rosalie, Larcher, Thibaut, Deschamps, Jack-Yves, Fusellier, Marion, Blouin, Véronique, Sevin, Caroline, Cartier, Nathalie, Adjali, Oumeya, Aubourg, Patrick, Moullier, Philippe, Colle, Marie-Anne
Format: Artigo
Langue:Inglês
Publié: American Society of Gene & Cell Therapy 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184633/
https://ncbi.nlm.nih.gov/pubmed/32355866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.04.001
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