Intra-CSF AAV9 and AAVrh10 Administration in Nonhuman Primates: Promising Routes and Vectors for Which Neurological Diseases?

The identification of the most efficient method for whole central nervous system targeting that is translatable to humans and the safest route of adeno-associated virus (AAV) administration is a major concern for future applications in clinics. Additionally, as many AAV serotypes were identified for...

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Publicado no:Mol Ther Methods Clin Dev
Main Authors: Bey, Karim, Deniaud, Johan, Dubreil, Laurence, Joussemet, Béatrice, Cristini, Joseph, Ciron, Carine, Hordeaux, Juliette, Le Boulc’h, Morwenn, Marche, Kevin, Maquigneau, Maud, Guilbaud, Michaël, Moreau, Rosalie, Larcher, Thibaut, Deschamps, Jack-Yves, Fusellier, Marion, Blouin, Véronique, Sevin, Caroline, Cartier, Nathalie, Adjali, Oumeya, Aubourg, Patrick, Moullier, Philippe, Colle, Marie-Anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184633/
https://ncbi.nlm.nih.gov/pubmed/32355866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.04.001
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