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The H2B ubiquitin-protein ligase RNF40 is required for somatic cell reprogramming

Direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) requires a resetting of the epigenome in order to facilitate a cell fate transition. Previous studies have shown that epigenetic modifying enzymes play a central role in controlling induced pluripotency and the generatio...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Xie, Wanhua, Miehe, Michaela, Laufer, Sandra, Johnsen, Steven A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184622/
https://ncbi.nlm.nih.gov/pubmed/32341358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2482-4
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