Immunoglobulin expression and the humoral immune response is regulated by the non-canonical poly(A) polymerase TENT5C

TENT5C is a non-canonical cytoplasmic poly(A) polymerase highly expressed by activated B cells to suppress their proliferation. Here we measure the global distribution of poly(A) tail lengths in responsive B cells using a Nanopore direct RNA-sequencing approach, showing that TENT5C polyadenylates im...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bilska, Aleksandra, Kusio-Kobiałka, Monika, Krawczyk, Paweł S., Gewartowska, Olga, Tarkowski, Bartosz, Kobyłecki, Kamil, Nowis, Dominika, Golab, Jakub, Gruchota, Jakub, Borsuk, Ewa, Dziembowski, Andrzej, Mroczek, Seweryn
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184606/
https://ncbi.nlm.nih.gov/pubmed/32341344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15835-3
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