Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy

BACKGROUND: Mouse models of mild spinal muscular atrophy (SMA) have been extremely challenging to generate. This paucity of model systems has limited our understanding of pathophysiological events in milder forms of the disease and of the effect of SMN depletion during aging. METHODS: A mild mouse m...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Deguise, Marc-Olivier, De Repentigny, Yves, Tierney, Alexandra, Beauvais, Ariane, Michaud, Jean, Chehade, Lucia, Thabet, Mohamed, Paul, Brittany, Reilly, Aoife, Gagnon, Sabrina, Renaud, Jean-Marc, Kothary, Rashmi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184161/
https://ncbi.nlm.nih.gov/pubmed/32339936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102750
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