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The lysine methyltransferase SMYD2 is required for normal lymphocyte development and survival of hematopoietic leukemias.
The 5 membered SET and MYND Domain-containing lysine methyltransferase (SMYD) family plays pivotal roles in development and proliferation. Initially characterized within the cardiovascular system, one such member, SMYD2, has been implicated as an oncogene in leukemias deriving from flawed hematopoie...
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| Publicado no: | Genes Immun |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183909/ https://ncbi.nlm.nih.gov/pubmed/32115575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-020-0094-8 |
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