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Rapid Postnatal Upregulation of Intestinal FXR-FGF19 Signaling in Premature Pigs

OBJECTIVES: Bile acid (BA) homeostasis is regulated by intestinal cellular signaling involving the farnesoid X receptor (FXR) and fibroblast growth factor 19 (FGF19) secretion. Using preterm and term pigs as a model, we examined postnatal changes in expression of the FXR-FGF19 axis that is poorly ch...

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Dades bibliogràfiques
Publicat a:J Pediatr Gastroenterol Nutr
Autors principals: Smith, Victoria, Jiang, Yanjun, Thymann, Thomas, Sangild, Per, Maj, Magdalena, Manjarin, Rodrigo, Burrin, Douglas
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183908/
https://ncbi.nlm.nih.gov/pubmed/31990866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0000000000002645
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