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Neurofilament light predicts decline in attention but not episodic memory in preclinical Alzheimer disease

BACKGROUND: Cerebrospinal fluid tau and neurofilament light (NfL) are two biomarkers of neurodegeneration in Alzheimer disease. Previous reports have shown that the influence of tau on cognitive decline depends on levels of amyloid burden whereas NfL predicts decline independently of amyloid. Most s...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Aschenbrenner, Andrew J., Gordon, Brian A., Fagan, Anne M., Schindler, Suzanne E., Balota, David A., Morris, John C., Hassenstab, Jason J.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183899/
https://ncbi.nlm.nih.gov/pubmed/32144992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200018
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