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Neurofilament light predicts decline in attention but not episodic memory in preclinical Alzheimer disease

BACKGROUND: Cerebrospinal fluid tau and neurofilament light (NfL) are two biomarkers of neurodegeneration in Alzheimer disease. Previous reports have shown that the influence of tau on cognitive decline depends on levels of amyloid burden whereas NfL predicts decline independently of amyloid. Most s...

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Bibliografische gegevens
Gepubliceerd in:J Alzheimers Dis
Hoofdauteurs: Aschenbrenner, Andrew J., Gordon, Brian A., Fagan, Anne M., Schindler, Suzanne E., Balota, David A., Morris, John C., Hassenstab, Jason J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183899/
https://ncbi.nlm.nih.gov/pubmed/32144992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200018
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