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Neurofilament light predicts decline in attention but not episodic memory in preclinical Alzheimer disease

BACKGROUND: Cerebrospinal fluid tau and neurofilament light (NfL) are two biomarkers of neurodegeneration in Alzheimer disease. Previous reports have shown that the influence of tau on cognitive decline depends on levels of amyloid burden whereas NfL predicts decline independently of amyloid. Most s...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Aschenbrenner, Andrew J., Gordon, Brian A., Fagan, Anne M., Schindler, Suzanne E., Balota, David A., Morris, John C., Hassenstab, Jason J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183899/
https://ncbi.nlm.nih.gov/pubmed/32144992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200018
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